Breadcrumb Home > Thesaurus > D Synonyms of downer Find synonyms for: Noun 1. sedative, sedative drug, depressant, downer, medicine, medication, medicament, medicinal drug, drug of abuse, street drug usage: a drug that reduces excitability and calms a person WordNet 3.0 Copyright © 2006 by Princeton University. All rights reserved.Definition and meaning of downer (Dictionary) TrendingHere are the facts and trivia that people are buzzing about. Hanukkah Origins of the Christmas Holiday Jewish Holidays, 2010-2030 (A.M. 5770-5791) Western Christian Holidays, 2010-2030 Krampus: The Christmas Devil Kwanzaa ✖ Related Content Daily Word Quiz: inmediasres Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language