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Tay-Sachs disease

(Encyclopedia) Tay-Sachs diseaseTay-Sachs diseasetāˈ-săksˈ [key], rare hereditary disease caused by a genetic mutation that leaves the body unable to produce an enzyme necessary for fat metabolism in…

in vitro fertilization

(Encyclopedia) in vitro fertilizationin vitro fertilizationvēˈtrō, vĭˈtrō [key] (IVF), technique for conception of a human embryo outside the mother's body. Several ova, or eggs, are removed from the…

Rodrigo, Joaquín

(Encyclopedia) Rodrigo, Joaquín, 1902–99, Spanish composer, b. Sagunto, Valencia. He lost his sight as a child and wrote his music in Braille. After his musical talent was recognized, Rodrigo studied…

Storey, David

(Encyclopedia) Storey, David (David Malcolm Storey), 1933–, English novelist and playwright, b. Wakefield, Yorkshire. His first novel, This Sporting Life (1960), was a disguised autobiography about…

Spinello di Luca Spinelli

(Encyclopedia) Spinello di Luca SpinelliSpinello di Luca Spinellispēnĕlˈlō dē l&oomacr;ˈkä spēnĕlˈlē [key], c.1346–1410, Italian painter, usually called Spinello Aretino from his birthplace,…

Barnardo, Thomas John

(Encyclopedia) Barnardo, Thomas JohnBarnardo, Thomas Johnbərnärˈdō [key], 1845–1905, British social reformer. Pioneering in the care of destitute children, he founded (1867) in London the East End…

Pesellino, Il

(Encyclopedia) Pesellino, IlPesellino, Ilēl pāzāl–lēˈnō [key], 1422–57, Italian painter of the Florentine school, whose real name was Francesco di Stefano. He was a grandson and pupil of Giuliano…

Parton, Dolly

(Encyclopedia) Parton, Dolly, 1946–, country singer, songwriter, and actress, b. Sevier County, Tenn. Among the most popular country singers of the 1970s and 80s, Parton is known for her Nashville-…

Kilpatrick, William Heard

(Encyclopedia) Kilpatrick, William HeardKilpatrick, William Heardkĭlpăˈtrĭk [key], 1871–1965, American philosopher, b. White Plains, Ga., grad. Mercer College, 1891, Ph.D. Columbia, 1912, and studied…

Keats, Ezra Jack

(Encyclopedia) Keats, Ezra Jack, 1916–83, American author and illustrator of children's books, b. Brooklyn, N.Y., as Jacob Ezra Katz. During the Great Depression, he painted murals for the Works…