Breadcrumb Home > Thesaurus > T Synonyms of trephine Find synonyms for: Noun 1. trepan, trephine, surgical instrument usage: a surgical instrument used to remove sections of bone from the skull Verb 1. trephine, operate on, operate usage: operate on with a trephine WordNet 3.0 Copyright © 2006 by Princeton University. All rights reserved.Definition and meaning of trephine (Dictionary) TrendingHere are the facts and trivia that people are buzzing about. Jewish Holidays, 2010-2030 (A.M. 5770-5791) Western Christian Holidays, 2010-2030 12 Steps to a New Year New Year's Resolution to Slim Down? Martin Luther King Speeches Books of the Bible: Old Testament Books in Order ✖ Related Content Daily Word Quiz: spurious Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language