Breadcrumb Home > Thesaurus > S Synonyms of spleen Find synonyms for: Noun 1. spleen, lien, lymphatic tissue, lymphoid tissue usage: a large dark-red oval organ on the left side of the body between the stomach and the diaphragm; produces cells involved in immune responses 2. irascibility, short temper, spleen, quick temper, bad temper, ill temper usage: a feeling of resentful anger WordNet 3.0 Copyright © 2006 by Princeton University. All rights reserved.Definition and meaning of spleen (Dictionary) TrendingHere are the facts and trivia that people are buzzing about. Hanukkah Origins of the Christmas Holiday Jewish Holidays, 2010-2030 (A.M. 5770-5791) Western Christian Holidays, 2010-2030 Krampus: The Christmas Devil Kwanzaa ✖ Related Content Daily Word Quiz: praedial Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language