Breadcrumb Home > Thesaurus > I Synonyms of issus Find synonyms for: Noun 1. Issus, battle of Issus usage: a battle (333 BC) in which Alexander the Great defeated the Persians under Darius III WordNet 3.0 Copyright © 2006 by Princeton University. All rights reserved.Definition and meaning of issus (Dictionary) TrendingHere are the facts and trivia that people are buzzing about. Hanukkah Origins of the Christmas Holiday Jewish Holidays, 2010-2030 (A.M. 5770-5791) Western Christian Holidays, 2010-2030 Krampus: The Christmas Devil Kwanzaa ✖ Related Content Daily Word Quiz: jactation Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language