Breadcrumb Home > Thesaurus > I Synonyms of isaac Find synonyms for: Noun 1. Isaac usage: (Old Testament) the second patriarch; son of Abraham and Sarah who was offered by Abraham as a sacrifice to God; father of Jacob and Esau WordNet 3.0 Copyright © 2006 by Princeton University. All rights reserved.Definition and meaning of isaac (Dictionary) TrendingHere are the facts and trivia that people are buzzing about. Hanukkah Origins of the Christmas Holiday Jewish Holidays, 2010-2030 (A.M. 5770-5791) Western Christian Holidays, 2010-2030 Krampus: The Christmas Devil Kwanzaa ✖ Related Content Daily Word Quiz: insitu Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language