Breadcrumb Home > Thesaurus > A Synonyms of afflict Find synonyms for: Verb 1. afflict, upset, discompose, untune, disconcert, discomfit usage: cause great unhappiness for; distress; "she was afflicted by the death of her parents" 2. afflict, smite, damage usage: cause physical pain or suffering in; "afflict with the plague" WordNet 3.0 Copyright © 2006 by Princeton University. All rights reserved.Definition and meaning of afflict (Dictionary) TrendingHere are the facts and trivia that people are buzzing about. Hanukkah Origins of the Christmas Holiday Jewish Holidays, 2010-2030 (A.M. 5770-5791) Western Christian Holidays, 2010-2030 Krampus: The Christmas Devil Kwanzaa ✖ Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language