Breadcrumb Home > Dictionary > Index L least squares: Meaning and Definition of Find definitions for: least' squares' Pronunciation: [key] — Statistics. Statistics. a method of estimating values from a set of observations by minimizing the sum of the squares of the differences between the observations and the values to be found. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. least significant digit least upper bound TrendingHere are the facts and trivia that people are buzzing about. Jewish Holidays, 2010-2030 (A.M. 5770-5791) Western Christian Holidays, 2010-2030 12 Steps to a New Year New Year's Resolution to Slim Down? Martin Luther King Speeches Books of the Bible: Old Testament Books in Order ✖ Related Content Daily Word Quiz: supererogatory Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language